Thursday, April 20, 2023

Sleeping pills and Alzheimer

Two seemingly conflicting reports about sleeping pills and Alzheimer:

1. Sleeping Pills May Increase Dementia Risk: Study https://www.webmd.com/sleep-disorders/news/20230303/sleeping-pills-may-increase-dementia-risk-study

2. Alzheimer’s Disease Protein Levels Reduced by Sleeping Pill https://www.insideprecisionmedicine.com/topics/patient-care/neurological-disorders/alzheimers-disease-protein-levels-reduced-by-sleeping-pill/

I think the key here is to make a distinction among these drugs. The good one (in the second article) is suvorexant, which according to a Google search, is sold under the brand name Belsomra. The bad ones (in the first article) are Dalmane (flurazepam), Halcion (triazolam), Rstoril (temazepam), Desyrel and Oleptro (trazodone), and Ambien (zolpidem). So if we ever need a sleeping pill, choose Belsomra and avoid the ones in the latter list.

But why bother? If I do need a sleeping pill, I'd rather take melatonin, which is naturally secreted in our body and has no truly harmful effect.